Tn 10 transposition in vivo: temporal separation of cleavages at the two transposon ends and roles of terminal basepairs subsequent to interaction of ends.

doi:10.1002/j.1460-2075.1994.tb06643.x

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Article

Tn 10 transposition in vivo: temporal separation of cleavages at the two transposon ends and roles of terminal basepairs subsequent to interaction of ends.

The EMBO journal - 15 Jul 1994

Haniford D, Kleckner N

Abstract excerpt

During Tn10 transposition, the transposon is fully excised from the donor site by double strand cleavages at the two ends of the element prior to integration at a new target site. Results presented here demonstrate that an interaction between the two transposon ends is required for double strand...

Topics

DNA Mutational Analysis
DNA Transposable Elements
DNA, Bacterial
Escherichia coli
Gene Rearrangement
Phenotype
Recombination, Genetic
Structure-Activity Relationship
Suppression, Genetic

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