Changes in chromatin morphology after infection of mouse embryo fibroblasts with polyoma virus, detected by image analysis.

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Article

Changes in chromatin morphology after infection of mouse embryo fibroblasts with polyoma virus, detected by image analysis.

Acta cytologica - 1 Jan 2000

Rowinski J, Sawicki W, Swenson R, Koprowski H

Abstract excerpt

Nuclear chromatin properties in control, SV40-infected and polyoma-infected cultures of mouse embryo fibroblasts were studied using quantitative image analysis. Distribution of Feulgen-DNA-content per nucleus was found to be similar in all three groups of cultures. No differences in nuclear area, mean optical density of chromatin and area of chromatin at different optical density thresholds were measurable...

Topics

Animals
Antigens, Viral
Cell Division
Cell Nucleus
Cell Transformation, Neoplastic
Cells, Cultured
Chromatin
Computers
DNA
DNA, Neoplasm
Densitometry
Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fluorescent Antibody Technique

Genetic Variation

Mice

Mice, Inbred ICR

Polyomavirus

Simian virus 40

Source

Open in PubMed

Identifiers

PMID: 47678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-47678-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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