Structure, diversity, and evolution of the T-cell receptor VB gene repertoire in primates.

doi:10.1007/BF00167078

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Article

Structure, diversity, and evolution of the T-cell receptor VB gene repertoire in primates.

Immunogenetics - 1 Jan 1994

Jaeger E E, Bontrop R E, Lanchbury J S

Abstract excerpt

AB T-cell receptors (TCR) that recognize major histocompatibility complex (MHC)/peptide antigen complexes regulate humoral and cellular arms of the adaptive immune response. Antigen binding sites of MHC and immunoglobulin heavy chain variable regions (Igh-V) are subject to diversity enhancing sel...

Topics

Amino Acid Sequence
Animals
Base Sequence
DNA Primers
Genetic Variation
Humans
Macaca mulatta
Male
Molecular Sequence Data
Pan troglodytes
Phylogeny
Receptors, Antigen, T-Cell, alpha-beta
Sequence Homology, Amino Acid

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