Article
The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells.
Journal of virology - 1 Aug 1994
Lodge R, Göttlinger H, Gabuzda D, Cohen E A, Lemay G
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) has been shown to exhibit a specific basolateral release in polarized epithelial cells. Previous investigators have used vaccinia virus recombinants expressing HIV proteins to demonstrate that virus release is nonpolarized in the absence of viral envelo...
Topics
- Animals
- Biological Transport
- Cell Line
- Cloning, Molecular
- Cytoplasm
- Dogs
- Gene Products, env
- Gene Products, gag
- HIV Antigens
- HIV Envelope Protein gp160
- HIV Envelope Protein gp41
- HIV-1
- Mutation
- Protein Precursors
- Protein Sorting Signals
- Viral Proteins
- Virus Replication
- gag Gene Products, Human Immunodeficiency Virus