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Article

Polarized human immunodeficiency virus budding in lymphocytes involves a tyrosine-based signal and favors cell-to-cell viral transmission.

Journal of virology - 1 Jun 1999

Deschambeault J, Lalonde J P, Cervantes-Acosta G, Lodge R, Cohen E A, Lemay G

Abstract excerpt

Maturation and release of human immunodeficiency virus type 1 (HIV-1) is targeted at the pseudopod of infected mononuclear cells. However, the intracellular mechanism or targeting signals leading to this polarized viral maturation are yet to be identified. We have recently demonstrated the presence of a functional YXXL motif for specific targeting of HIV-1 virions to the basolateral membrane surface in polarized...

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Identifiers

PMID: 10233963
DOI: 10.1128/JVI.73.6.5010-5017.1999
PMCID: PMC112545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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