Article
Genomic instability of microsatellite repeats and mutations of H-, K-, and N-ras, and p53 genes in renal cell carcinoma.
Cancer research - 15 Jul 1994
Uchida T, Wada C, Wang C, Egawa S, Ohtani H, Koshiba K
Abstract excerpt
Thirty-six primary renal cell carcinoma samples and one metastatic lymph node DNA sample were examined for mutations of H-, K-, and N-ras and p53 genes, and genomic instability at (AC)n, (CA)n.(GT)n, and (TA)n.(GT)n repeats. No mutations were noted for H-, K-, and N-ras genes and only 2 of all th...
Topics
- Base Sequence
- Carcinoma, Renal Cell
- DNA, Satellite
- Genes, p53
- Genes, ras
- Humans
- Kidney Neoplasms
- Molecular Sequence Data
- Mutation