Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic instability in multistage carcinogenesis.

Toxicology letters - 15 Mar 2000

Yamasaki H, Mironov N

Abstract excerpt

For a normal cell to accumulate multiple genetic changes during multistage carcinogenesis, the induction of genomic instability is considered advantageous. Since most human cancers are associated with exposure to environmental carcinogens, it is likely that environmental carcinogens interact with genomic instability. Our results indeed suggest that carcinogens contribute to the induction of microsatellite...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pair Mismatch
Share to Carcinogens, Environmental
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to HeLa Cells

Share to Microsatellite Repeats

Share to Neoplasms

Source

Identifiers

PMID: 10720739
DOI: 10.1016/s0378-4274(99)00278-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic instability in multistage carcinogenesis.PMID 10720739Read ↗

Multiple mutations in human cancers.Semantic proximity Read ↗

Microsatellite instability in human cancer.Semantic proximity Read ↗

Genetic instability in human tumors.Semantic proximity Read ↗

Destructive cycles: the role of genomic instability and adaptation in carcinogenesis.Semantic proximity Read ↗

[Microsatellite instability: a potential tool for the study of life sciences].Semantic proximity Read ↗

[What's new about microsatellite instability significance in human carcinogenesis?].Semantic proximity Read ↗

Significance of multiple mutations in cancer.Semantic proximity Read ↗

Multiple genetic alterations in human carcinogenesis.Semantic proximity Read ↗

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation.Semantic proximity Read ↗

Genomic instability and radiation.Semantic proximity Read ↗

Role of genomic instability in arsenic-induced carcinogenicity. A review.Semantic proximity Read ↗

Genomic stability and tumorigenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.