Article
Characterization of nickel-induced mutations.
The Science of the total environment - 6 Jun 1994
Rossetto F E, Turnbull J D, Nieboer E
Abstract excerpt
A Chinese hamster ovary cell line (designated AS52) has been used to test the mutagenicity of nickel compounds. This line lacks the endogenous gene for hypoxanthine phosphoribosyl transferase (HPRT) but contains an inserted bacterial gene coding for the enzyme guanine-hypoxanthine phosphoribosyl...
Topics
- Animals
- Base Sequence
- CHO Cells
- Cricetinae
- Gene Deletion
- Molecular Sequence Data
- Mutagenicity Tests
- Mutation
- Nickel
- Point Mutation
