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Induction of genetic instability and chromosomal instability by nickel sulfate in V79 Chinese hamster cells.

Mutagenesis - 1 Mar 2003

Ohshima Susumu

Abstract excerpt

Nickel compounds are known to be carcinogenic to humans and show genotoxicity, including the ability to induce chromosome aberrations and neoplastic transformation in vitro. The mutagenicity of nickel compounds is, however, equivocal and the mechanisms of carcinogenesis are still not clear. In this study, the possibility that nickel compounds induce genetic or chromosomal instability was examined, because recent...

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Identifiers

PMID: 12621068
DOI: 10.1093/mutage/18.2.133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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