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Article

Direct and indirect effects of mutations in lambda PRM on open complex formation at the divergent PR promoter.

Journal of molecular biology - 8 Jul 1994

Fong R S, Woody S, Gussin G N

Abstract excerpt

A detailed kinetic analysis demonstrates that, in vitro, mutations in the PRM promoter of bacteriophage lambda can increase the rate of open complex formation at the divergent, lytic promoter PR in either of two ways. (1) PRM- mutations, typified by PRMKM11, indirectly stimulate PR by eliminating interference from RNA polymerase (RNAP) molecules bound at wild-type PRM. This effect can be observed only when PR is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8027996
DOI: 10.1006/jmbi.1994.1426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Direct and indirect effects of mutations in lambda PRM on open complex formation at the divergent PR promoter.PMID 8027996Read ↗

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New Insights into the Phage Genetic Switch: Effects of Bacteriophage Lambda Operator Mutations on DNA Looping and Regulation of PR, PL, and PRM.Semantic proximity Read ↗

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Repression of transcription initiation at 434 P(R) by 434 repressor: effects on transition of a closed to an open promoter complex.Semantic proximity Read ↗

The DnaK-DnaJ-GrpE chaperone system activates inert wild type pi initiator protein of R6K into a form active in replication initiation.Semantic proximity Read ↗

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