Direct and indirect effects of mutations in lambda PRM on open complex formation at the divergent PR promoter.

doi:10.1006/jmbi.1994.1426

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Article

Direct and indirect effects of mutations in lambda PRM on open complex formation at the divergent PR promoter.

Journal of molecular biology - 8 Jul 1994

Fong R S, Woody S, Gussin G N

Abstract excerpt

A detailed kinetic analysis demonstrates that, in vitro, mutations in the PRM promoter of bacteriophage lambda can increase the rate of open complex formation at the divergent, lytic promoter PR in either of two ways. (1) PRM- mutations, typified by PRMKM11, indirectly stimulate PR by eliminating...

Topics

Bacteriophage lambda
Base Sequence
DNA, Viral
DNA-Directed RNA Polymerases
Kinetics
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Transcription, Genetic

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