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Article

Dual role for transactivator protein C in activation of mom promoter of bacteriophage Mu.

The Journal of biological chemistry - 31 Mar 2006

Chakraborty Atanu, Nagaraja Valakunja

Abstract excerpt

Transactivator C protein of bacteriophage Mu activates the mom gene of the phage by an unusual mechanism. DNA binding by C to its site results in unwinding of the neighboring sequences, realigning the out-of-phase promoter elements to facilitate RNA polymerase (RNAP) binding. High level stimulation of a C-independent constitutive promoter mutant (where RNAP is already bound) by the transactivator suggested an...

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PMID: 16446361
DOI: 10.1074/jbc.M512906200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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