Article
Interference by PR-bound RNA polymerase with PRM function in vitro. Modulation by the bacteriophage lambda cI protein.
The Journal of biological chemistry - 25 Apr 1993
Hershberger P A, Mita B C, Tripatara A, deHaseth P L
Abstract excerpt
Activation of the weak PRM promoter by cI protein is an essential process in the establishment of lysogeny. Much evidence has accumulated that cI protein binds cooperatively to the operators OR1 and OR2 and that protein at the OR2 site contacts RNA polymerase to facilitate open complex formation...
Topics
- Bacteriophage lambda
- Base Sequence
- Cloning, Molecular
- DNA, Viral
- DNA-Binding Proteins
- DNA-Directed RNA Polymerases
- Molecular Sequence Data
- Mutation
- Operator Regions, Genetic
- Promoter Regions, Genetic
- Repressor Proteins
- Temperature
- Transcription Factors
- Viral Proteins
- Viral Regulatory and Accessory Proteins