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Article

Pit-1 gene expression in the human pituitary and pituitary adenomas.

1 Jul 1994

Abstract excerpt

The cellular basis for pituitary neoplasia is poorly understood. The POU domain protein Pit-1 is a pituitary-specific transcription factor involved in the generation, differentiation, and proliferation of three pituitary cell types: lactotrophs, somatotrophs, and thyrotrophs. In this study, we analyzed the expression of Pit-1 gene in a series of 15 different human pituitary tumors and compared it with that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8027225
DOI: 10.1210/jcem.79.1.8027225

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