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Article

Pit-1 is expressed in normal and tumorous human breast and regulates GH secretion and cell proliferation

1 Aug 2005

Abstract excerpt

BACKGROUND: The transcription factor pituitary-1 (Pit-1) is mainly expressed in the pituitary gland, where it has critical roles in cell differentiation and as a transcriptional factor for GH and prolactin (PRL). It is also expressed in human extrapituitary tissues (placenta, lymphoid and haematopoietic tissues) and cell lines (human breast adenocarcinoma cells, MCF-7). Despite the widely suggested roles of GH...

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Share to Growth Hormone and Insulin-like Growth Factors
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Identifiers

PMID: 16061841
DOI: 10.1530/eje.1.01962

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