Article
A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity.
The Journal of biological chemistry - 8 Jul 1994
Mueckler M, Kruse M, Strube M, Riggs A C, Chiu K C, Permutt M A
Abstract excerpt
Glut2, the facilitative glucose transporter isoform expressed in pancreatic beta cells, is believed to play a role in glucose-stimulated insulin secretion. Two polymorphisms that result in amino acid substitutions have been reported in the human Glut2 gene (Tanizawa, Y., Riggs, A. C., Chiu, K. C., Janssen, R. C., Bell, D. S. H., Go, R. P. C., Roseman, J. M., Acton, R. T., and Permutt, M. A. (1994) Diabetologia...
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