Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.

doi:10.2337/diab.41.11.1436

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Article

Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.

Diabetes - 1 Nov 1992

Buse J B, Yasuda K, Lay T P, Seo T S, Olson A L, Pessin J E, Karam J H, Seino S, Bell G I

Abstract excerpt

Four overlapping DNA fragments spanning 32 kb containing the human GLUT4 facilitative glucose-transporter gene were isolated and characterized. The sequence of the GLUT4 gene (approximately 6.3 kb) and 2.0 kb of the promoter region was determined. The sequence of the promoter revealed potential binding sites for transcription factors known to regulate gene expression in muscle cells and adipocytes. However,...

Topics

3T3 Cells
Adipose Tissue
Adult
Amino Acid Sequence
Animals
Base Sequence
DNA
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Exons
Gene Library
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Indians, North American

Liver

Mice

Molecular Sequence Data

Monosaccharide Transport Proteins

Source

Open in PubMed

Identifiers

PMID: 1397719
DOI: 10.2337/diab.41.11.1436

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1397719-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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