Article
Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits.
Diabetes - 1 Sept 2003
Andersen Gitte, Rose Christian Schack, Hamid Yasmin Hassan, Drivsholm Thomas, Borch-Johnsen Knut, Hansen Torben, Pedersen Oluf
Abstract excerpt
The SLC2A10 gene encodes the GLUT10 facilitative glucose transporter, which is expressed in high amounts in liver and pancreas. The gene is mapped to chromosome 20q12-q13.1, a region that has been shown to be linked to type 2 diabetes. The gene was examined in 61 Danish type 2 diabetic patients, and a total of six variants (-27C-->T, Ala206Thr, Ala272Ala, IVS2 + 10G-->A, IVS4 + 18T-->G, and IVS4 + 26G-->A) were...
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