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Article

Genotype effects on the antioxidant enzymes activity and mRNA expression in liver and kidney tissues of autoimmune-prone MRL/MpJ-lpr/lpr mice.

Biochimica et biophysica acta - 14 Jul 1994

Venkatraman J T, Chandrasekar B, Kim J D, Fernandes G

Abstract excerpt

Congeneic pairs of MRL/lpr and MRL/++ (+/+) mice differ in incidence of autoantibodies, lymphoproliferative disease and survival, characteristics that are linked to immunological abnormalities. MRL/lpr mice have a significantly shorter life span compared to +/+ mice. Because a weak antioxidant de...

Topics

Animals
Antibodies, Anticardiolipin
Antioxidants
Autoimmune Diseases
Body Weight
Fatty Acids
Female
Gene Expression Regulation, Enzymologic
Genotype
In Vitro Techniques
Kidney
Lipid Peroxidation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver

Mice

Mice, Inbred Strains

RNA, Messenger

Source

Identifiers

PMID: 8025127
DOI: 10.1016/0005-2760(94)90023-x

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8025127-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Genotype effects on the antioxidant enzymes activity and mRNA expression in liver and kidney tissues of autoimmune-prone MRL/MpJ-lpr/lpr mice.PMID 8025127Read ↗

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