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Article

Functional redundancy: the respective roles of the two sloppy paired genes in Drosophila segmentation.

Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 1994

Cadigan K M, Grossniklaus U, Gehring W J

Abstract excerpt

The sloppy paired (slp) locus consists of two genes, slp1 and slp2, both of which encode proteins containing a forkhead domain (a DNA-binding motif). Previous work has shown that a severe segmentation phenotype is obtained only when both slp genes are deleted. Here we examine the functional redundancy of the locus in more detail. The phenotypes of embryos containing various combinations of functional slp genes...

Topics

Animals
Cloning, Molecular
Drosophila
Embryo, Nonmammalian
Gene Expression
Heat-Shock Proteins
Homozygote
In Situ Hybridization
Multigene Family
Phenotype
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8022780
DOI: 10.1073/pnas.91.14.6324
PMCID: PMC44194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8022780-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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