Article
Replacement of diaminopimelic acid by cystathionine or lanthionine in the peptidoglycan of Escherichia coli.
Journal of bacteriology - 1 Jul 1994
Mengin-Lecreulx D, Blanot D, van Heijenoort J
Abstract excerpt
In Escherichia coli, auxotrophy for diaminopimelic acid (A2pm) can be suppressed by growth with exogenous cystathionine or lanthionine. The incorporation of cystathionine into peptidoglycan metabolism was examined with a dapA metC mutant, whereas for lanthionine, a dapA metA mutant strain was used. Analysis of peptidoglycan precursors and sacculi isolated from cells grown with epimeric cystathionine or...
Topics
- Alanine
- Amino Acid Sequence
- Cystathionine
- Diaminopimelic Acid
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Oligopeptides
- Peptide Synthases
- Peptidoglycan
- Substrate Specificity
