Article
Control of methionine biosynthesis in Escherichia coli K12: a closer study with analogue-resistant mutants.
Journal of general microbiology - 1 Mar 1991
Chattopadhyay M K, Ghosh A K, Sengupta S
Abstract excerpt
Control of methionine biosynthesis in Escherichia coli K12 was reinvestigated by using methionine-analogue-resistant mutants. Norleucine (NL) and alpha-methylmethionine (MM) were found to inhibit methionine biosynthesis directly whereas ethionine (Et) competitively inhibited methionine utilization. Adenosylation of Et to generate S-adenosylethionine (AdoEt) by cell-free enzyme from E. coli K12 was demonstrated....
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