Article
The molecular genetics of autoimmune liver disease.
Hepatology (Baltimore, Md.) - 1 Jul 1994
Donaldson P, Doherty D, Underhill J, Williams R
Abstract excerpt
The dual observations that human leukocyte antigens have an antigen-binding groove and that the polymorphism we study as human leukocyte antigen types is largely related to amino acid substitutions in and around that groove have provided a new focus for immunogenetic studies. In autoimmune liver...
Topics
- Autoimmune Diseases
- Cholangitis, Sclerosing
- Chromosomes, Human, Pair 6
- Genes, MHC Class I
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DR Antigens
- Hepatitis
- Humans
- Liver Cirrhosis, Biliary
- Liver Diseases
- T-Lymphocytes