Article
The molecular genetics of autoimmune liver disease.
Hepatology (Baltimore, Md.) - 1 Jul 1994
Donaldson P, Doherty D, Underhill J, Williams R
Abstract excerpt
The dual observations that human leukocyte antigens have an antigen-binding groove and that the polymorphism we study as human leukocyte antigen types is largely related to amino acid substitutions in and around that groove have provided a new focus for immunogenetic studies. In autoimmune liver disease, recent studies have described specific amino acid substitutions in the antigen-binding groove of human...
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