Article
Paths to understanding the genetic basis of autoimmune disease.
Nature - 2 Jun 2005
Rioux John D, Abbas Abul K
Abstract excerpt
Some people inherit an unfortunate combination of genetic sequences, such that exposure to an external trigger causes their immune response to turn on their own tissues. Although mutations in a single gene can cause autoimmunity, most autoimmune diseases are associated with several sequence variants. Marked advances in genetic resources and tools are now making it possible to identify the sequence variants that...
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