Article
The genetic basis of immune and autoimmune responses.
Acta paediatrica (Oslo, Norway : 1992). Supplement - 1 May 2004
Bottazzo G F, Locatelli M, Fierabracci A, Fruci D
Abstract excerpt
HLA class I and class II molecules play a major role in the presentation of short, pathogen-derived peptides to T cells, a process that initiates the adaptive cellular and humoral immune responses. However, the factors governing a cell's ability to respond or not to particular peptides are still not completely understood. Taking the example of a viral infection, in tissues infected with a virus, viral particles...
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