Article
Human leukocyte antigen class II alleles in white Brazilian patients with celiac disease.
Journal of pediatric gastroenterology and nutrition - 1 Oct 2000
Silva E M, Fernandes M I, Galvão L C, Sawamura R, Donadi E A
Abstract excerpt
BACKGROUND: Celiac disease (CD) is a permanent gluten intolerance disorder characterized by malabsorption, intestinal mucosa villus atrophy, and crypt hyperplasia. Clinical and histologic features improve in persons consuming a gluten free diet. The pathogenesis of CD involves environmental, genetic, and immunologic factors. METHODS: The frequencies of human leukocyte antigen (HLA) class II alleles were evaluated...
Topics
- Alleles
- Brazil
- Case-Control Studies
- Celiac Disease
- Female
- Gene Frequency
- Genes, Recessive
- Genetic Predisposition to Disease
- Genotype
- HLA-D Antigens
- Humans
- Male
- White People
