Article
Parthenogenetic activation of oocytes in c-mos-deficient mice.
Nature - 7 Jul 1994
Hashimoto N, Watanabe N, Furuta Y, Tamemoto H, Sagata N, Yokoyama M, Okazaki K, Nagayoshi M, Takeda N, Ikawa Y
Abstract excerpt
In Xenopus the c-mos proto-oncogene product (Mos) is essential for the initiation of oocyte maturation, for the progression from meiosis I to meiosis II and for the second meiotic metaphase arrest, acting as an essential component of the cytostatic factor CSF. Its function in mouse oocytes is unc...
Topics
- Animals
- Cells, Cultured
- Chorionic Gonadotropin
- Crosses, Genetic
- Female
- Fertility
- Genes, mos
- Male
- Meiosis
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Mutation
- Oocytes
- Oogenesis
- Ovarian Neoplasms
- Parthenogenesis
- Proto-Oncogene Proteins c-mos
