Article
Parthenogenetic activation of oocytes in c-mos-deficient mice.
Nature - 7 Jul 1994
Hashimoto N, Watanabe N, Furuta Y, Tamemoto H, Sagata N, Yokoyama M, Okazaki K, Nagayoshi M, Takeda N, Ikawa Y
Abstract excerpt
In Xenopus the c-mos proto-oncogene product (Mos) is essential for the initiation of oocyte maturation, for the progression from meiosis I to meiosis II and for the second meiotic metaphase arrest, acting as an essential component of the cytostatic factor CSF. Its function in mouse oocytes is unclear, however, as is the biological significance of c-mos mRNA expression in testes and several somatic tissues. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.