Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

What does mos do in oocytes and somatic cells?

1 Jan 1997

Abstract excerpt

Mos, a protein kinase, is specifically expressed and functions during meiotic maturation (or G2/M progression) of vertebrate oocytes. When expressed ectopically, however, it can also readily induce oncogenic transformation (or uncontrolled G1/S transitions) in somatic cells. In both of these cell types, Mos activates mitogen-activated protein kinase (MAPK), which seems largely to mediate its different functions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Kruppel-like factors research
Share to Microtubule and mitosis dynamics
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9008413
DOI: 10.1002/bies.950190105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

What does mos do in oocytes and somatic cells?PMID 9008413Read ↗

Mos and the cell cycle: the molecular basis of the transformed phenotype.Semantic proximity Read ↗

Similarities between somatic cells overexpressing the mos oncogene and oocytes during meiotic interphase.Semantic proximity Read ↗

Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation.Semantic proximity Read ↗

Meiotic abnormalities of c-mos knockout mouse oocytes: activation after first meiosis or entrance into third meiotic metaphase.Semantic proximity Read ↗

MOS mutation causes female infertility with large polar body oocytes.Semantic proximity Read ↗

The molecular mechanisms of oocyte maturation and early embryonic development are unveiling new insights into reproductive medicineSemantic proximity Read ↗

Regulation of meiotic maturation in the mammalian oocyte: Inteplay between exogenous cues and the microtubule cytoskeletonSemantic proximity Read ↗

Role of Mitogen Activated Protein Kinase and Maturation Promoting Factor During the Achievement of Meiotic Competency in Mammalian OocytesSemantic proximity Read ↗

Mos/mitogen-activated protein kinase can induce early meiotic phenotypes in the absence of maturation-promoting factor: a novel system for analyzing spindle formation during meiosis I.Semantic proximity Read ↗

Bi-allelic mutations in MOS cause female infertility characterized by preimplantation embryonic arrest.Semantic proximity Read ↗

Parthenogenetic activation of oocytes in c-mos-deficient mice.Semantic proximity Read ↗

Mechanisms Regulating Oocyte Meiotic Resumption: Roles of Mitogen-Activated Protein KinaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.