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Article

Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs.

Nature - 7 Jul 1994

Colledge W H, Carlton M B, Udy G B, Evans M J

Abstract excerpt

The c-mos proto-oncogene encodes a 37-39K cytoplasmic serine/threonine kinase implicated in the meiotic maturation events during murine spermatogenesis and oogenesis. In Xenopus, ectopic expression of pp39mos can promote both the meiotic maturation of oocytes and also arrest the cleavage of blastomeres. To elucidate the role of pp39mos we have generated homozygous mutant mice by gene targeting in embryonic stem...

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Identifiers

PMID: 8015609
DOI: 10.1038/370065a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs.PMID 8015609Read ↗

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