Article
Antibiotic treatment of experimental endocarditis due to methicillin-resistant Staphylococcus epidermidis.
The Journal of infectious diseases - 1 Jul 1994
Entenza J M, Fluckiger U, Glauser M P, Moreillon P
Abstract excerpt
The natural history and treatment of experimental endocarditis due to heterogeneous and homogeneous methicillin-resistant Staphylococcus epidermidis was investigated. Amoxicillin/clavulanate or vancomycin were administered for 3 days via a computerized pump to mimic human drug kinetics in animals. After challenge with the minimum inoculum producing 90% of infections (ID90), bacteria in the vegetations grew...
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