Article
Linezolid therapy of vancomycin-resistant Enterococcus faecium experimental endocarditis.
Antimicrobial agents and chemotherapy - 1 Feb 2001
Patel R, Rouse M S, Piper K E, Steckelberg J M
Abstract excerpt
We compared the activities of linezolid (25 mg/kg of body weight, administered intraperitoneally every 8 h) and of vancomycin (25 mg/kg of body weight, administered intraperitoneally every 8 h) in a rat model of vanA vancomycin-resistant Enterococcus faecium experimental endocarditis. Results were expressed as median log(10) CFU per gram of vegetation after 3 days of treatment. The median log(10) CFU per gram of...
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