Article
Investigation of methicillin-resistant Staphylococcus aureus showing reduced vancomycin susceptibility isolated from a patient with infective endocarditis.
International journal of antimicrobial agents - 1 Dec 2003
Takayama Yoko, Hanaki Hideaki, Irinoda Kazuhiko, Kokubun Hideya, Yoshida Kazunari, Sunakawa Keisuke
Abstract excerpt
A patient with infective endocarditis (IE) caused by methicillin-resistant Staphylococcus aureus (MRSA) was treated with vancomycin (VAN). VAN was ineffective, although therapeutic drug monitoring (TDM) indicated that the recommended trough level was maintained. Five MRSA isolates obtained at various times were analyzed to determine the minimum inhibitory concentration (MIC) and were subjected to population...
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