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Article

Presence of p53 mutations in 3Y1-B clone 1-6: a rat cell line widely used as a normal immortalized fibroblast.

Japanese journal of cancer research : Gann - 1 May 1994

Ushijima T, Makino H, Nakayasu M, Aonuma S, Takeuchi M, Segawa K, Sugimura T, Nagao M

Abstract excerpt

The 3Y1 cell line, established from a rat whole embryo, is widely used as a normal immortalized fibroblast. We analyzed p53 mutations in four clonal lines derived from the 3Y1 cell line; 3Y1-B clone 1-6, 3Y1-C and two clonal lines (3Y1 cl-3 and 3Y1 cl-6) which had been transformed by the human papilloma virus E6 gene. Polymerase chain reaction (PCR)-single strand conformation polymorphism (SSCP) analysis and DNA...

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Identifiers

PMID: 8014101
DOI: 10.1111/j.1349-7006.1994.tb02379.x
PMCID: PMC5919488

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