Article
Spontaneous establishment of a novel Japanese macaque cell line with epithelial cell phenotypes.
In vitro cellular & developmental biology. Animal - 1 Jun 2002
Shimizu Yuko, Ishida Takafumi
Abstract excerpt
A novel macaque cell line (J3K) with epithelial phenotypes was spontaneously established from a kidney specimen of a Japanese macaque (Macaca fuscata). Its population doubling level reached more than 500, and it was regarded as an established permanent cell line. J3K cells have transformed cell phenotypes such as loss of contact inhibition and anchorage-independent cell growth. Unlike other monkey adherent cell...
Topics
- Animals
- Base Sequence
- Cell Adhesion
- Cell Culture Techniques
- Cell Differentiation
- Cell Division
- Cell Line
- Cell Transformation, Neoplastic
- Epithelial Cells
- Gene Expression Regulation, Neoplastic
- Japan
- Macaca fascicularis
- Models, Genetic
- Molecular Sequence Data
- Phenotype
- Telomerase
- Telomere
- Tumor Suppressor Protein p53