Article
Robust genetic linkage analysis based on a score test of homogeneity: the weighted pairwise correlation statistic.
Genetic epidemiology - 1 Jan 1994
Commenges D
Abstract excerpt
In testing genetic linkage using large or complex pedigrees, robust methods may be preferred to the Lod-score method. The affected-pedigree-member method is robust but does not use the information available in nonaffected subjects, which results in a loss of power. We propose a new test of geneti...
Topics
- Age of Onset
- Alleles
- Genetic Linkage
- Humans
- Models, Genetic
- Pedigree
- Statistics as Topic