Article
Twin Research in the Post-Genomic Era: Dissecting the Pathophysiological Effects of Adversity and the Social Environment.
International journal of molecular sciences - 29 Apr 2020
Turner Jonathan D, D'Ambrosio Conchita, Vögele Claus, Diewald Martin
Abstract excerpt
The role of twins in research is evolving as we move further into the post-genomic era. With the re-definition of what a gene is, it is becoming clear that biological family members who share a specific genetic variant may well not have a similar risk for future disease. This has somewhat invalidated the prior rationale for twin studies. Case co-twin study designs, however, are slowly emerging as the ideal tool...
Topics
- Disease Susceptibility
- Diseases in Twins
- Epigenesis, Genetic
- Genetic Predisposition to Disease
- Genetic Research
- Genetics, Medical
- Genomics
- Humans
- Social Environment
- Twins
- Twins, Dizygotic