Article
H-ras mutation detection in bladder cancer by COLD-PCR analysis and direct sequencing.
Urologia internationalis - 1 Jan 2012
Wang Ai-Xiang, Chang Ji-Wu, Li Chang-Ying, Liu Kun, Lin Ying-Li
Abstract excerpt
OBJECTIVE: A sensitive mutation detection method called co-amplification at lower denaturation temperature-polymerase chain reaction (COLD-PCR) was applied to improve the detection frequencies of expressive mutations in the H-ras gene, including exons 1 and 2, in a group of Chinese patients diagnosed with bladder cancer. MATERIALS AND METHODS: The expressive mutations in the H-ras gene in 86 fresh tissues of...
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