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Article

Genetic and structural evidence for antigen selection of anti-DNA antibodies.

Annual review of immunology - 1 Jan 1994

Radic M Z, Weigert M

Abstract excerpt

The primary structure of anti-DNA antibodies is highly diverse, a result of different germline variable (V) gene use, different combinations of immunoglobulin gene segments, peculiar heavy chain complementarity determining region 3 (H-CDR3) segments, and somatic mutations. Nevertheless, tertiary structure predictions reveal common features that yield information about likely contact sites in the anti-DNA...

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Source

Identifiers

PMID: 8011289
DOI: 10.1146/annurev.iy.12.040194.002415

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Source receipt: pubmed, retrieved 7 Sept 2026.

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