Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel allele of HAP1 causes uninducible expression of HEM13 in Saccharomyces cerevisiae.

Genetics - 1 Mar 1994

Ushinsky S C, Keng T

Abstract excerpt

Transcription of HEM13 in Saccharomyces cerevisiae is repressed by heme and oxygen. We have isolated two mutants in which expression of HEM13 is aberrant. The mutant alleles in these strains represent two different alleles of HAP1. HAP1 encodes an activator protein whose DNA binding activity is stimulated by heme, and is required for the transcription of CYC1, ROX1 and a number of other heme-dependent genes. One...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to DNA Primers

Share to Molecular Sequence Data

Share to Phenotype

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8005437
DOI: 10.1093/genetics/136.3.819
PMCID: PMC1205888

Genes

HAP1
CYC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel allele of HAP1 causes uninducible expression of HEM13 in Saccharomyces cerevisiae.PMID 8005437Read ↗

Transcript analysis of 203 novel genes from Saccharomyces cerevisiae in hap1 and rox1 mutant backgrounds.Semantic proximity Read ↗

A microarray-assisted screen for potential Hap1 and Rox1 target genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Functional analysis of heme regulatory elements of the transcriptional activator Hap1.Semantic proximity Read ↗

Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication.Semantic proximity Read ↗

Characterization of mutations that suppress the temperature-sensitive growth of the hpr1 delta mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

The yeast transcriptome in aerobic and hypoxic conditions: effects of hap1, rox1, rox3 and srb10 deletions.Semantic proximity Read ↗

The transcriptional activator HAP4 is a high copy suppressor of an oxa1 yeast mutation.Semantic proximity Read ↗

HAM1, the gene controlling 6-N-hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast.Semantic proximity Read ↗

The HIR4-1 mutation defines a new class of histone regulatory genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

REO1 and ROX1 are alleles of the same gene which encodes a transcriptional repressor of hypoxic genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

YHP1 encodes a new homeoprotein that binds to the IME1 promoter in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.