Article
A novel allele of HAP1 causes uninducible expression of HEM13 in Saccharomyces cerevisiae.
Genetics - 1 Mar 1994
Ushinsky S C, Keng T
Abstract excerpt
Transcription of HEM13 in Saccharomyces cerevisiae is repressed by heme and oxygen. We have isolated two mutants in which expression of HEM13 is aberrant. The mutant alleles in these strains represent two different alleles of HAP1. HAP1 encodes an activator protein whose DNA binding activity is s...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- DNA Primers
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression
- Genes, Fungal
- Genetic Complementation Test
- Heme
- Molecular Sequence Data
- Mutagenesis
- Oxygen
- Phenotype
- Plasmids
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins