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Article

T-cell maturation and clonal deletion in cyclosporine-induced autoimmunity.

Journal of autoimmunity - 1 Apr 1991

Prud'homme G J, Sanders R, Parfrey N A, Ste-Croix H

Abstract excerpt

In some circumstances cyclosporine (CyA) induces autoimmune phenomena, and a lethal form of syngeneic graft-vs-host disease (SGVHD) can be induced in rats by the administration of CyA. Although several rat strains develop this disease, in this study, we report that of six mouse strains tested, only the DBA/2 strain developed SGVHD. A comparison of the effect of CyA on thymocytic and peripheral T-cell populations...

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Identifiers

PMID: 1652970
DOI: 10.1016/0896-8411(91)90030-g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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