Article
Evidence that cyclosporine treatment causes the appearance in rat lymph node of T cells having the antigenic phenotypes of cortical thymocytes.
Transplantation - 1 Mar 1991
Chen-Woan M, Goldschneider I
Abstract excerpt
The antigenic phenotypes and relative size distributions of thymocytes and LN cells from young adult M520 strain rats, injected s.c. with cyclosporine (15 mgm/kg) for 10 consecutive days, were determined by FACS analysis and fluorescence microscopy. In addition, the prothymocyte activity in BM from these CsA-treated rats was assayed by i.v. adoptive transfer into sublethally irradiated, but non-CsA-treated, BUF...
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