Article
Evidence that cyclosporine treatment causes the appearance in rat lymph node of T cells having the antigenic phenotypes of cortical thymocytes.
Transplantation - 1 Mar 1991
Chen-Woan M, Goldschneider I
Abstract excerpt
The antigenic phenotypes and relative size distributions of thymocytes and LN cells from young adult M520 strain rats, injected s.c. with cyclosporine (15 mgm/kg) for 10 consecutive days, were determined by FACS analysis and fluorescence microscopy. In addition, the prothymocyte activity in BM fr...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Surface
- CD4 Antigens
- CD8 Antigens
- Cyclosporins
- Female
- Flow Cytometry
- Lymph Nodes
- Phenotype
- Rats
- Rats, Inbred Strains
- T-Lymphocyte Subsets
- T-Lymphocytes
- Thy-1 Antigens
- Thymus Gland