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Genetic polymorphism of cytochrome P4502E1 in a Swedish population

22 Mar 1993

Abstract excerpt

Genetic polymorphism of CYP2E1 was investigated among 195 Swedish patients with lung cancer and 206 controls. Three different polymorphic sites were found, all in introns, using RFLP and the restriction enzymes DraI, RsaI and TaqI. The frequencies of the rare alleles were 0.08-0.18 and much lower than previously described among Japanese. No significant difference in distribution of the polymorphic alleles between...

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PMID: 8096192
DOI: 10.1016/0014-5793(93)80547-8

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