Article
NA gene frequencies in the German population, determined by polymerase chain reaction with sequence-specific primers.
Transfusion - 1 Jan 1995
Bux J, Stein E L, Santoso S, Mueller-Eckhardt C
Abstract excerpt
BACKGROUND: The granulocyte antigens NA1 and NA2 are often targets of granulocyte antibodies causing immune neutropenia. Currently, NA typing relies on the properties of the typing sera or antibodies and the techniques used. Therefore, the technique of polymerase chain reaction with sequence-specific primers (PCR-SSP) was adapted for DNA-based NA typing and was used for determining the NA gene frequencies in the...
Topics
- Base Sequence
- Gene Amplification
- Gene Frequency
- Genotype
- Germany
- Humans
- Isoantigens
- Molecular Sequence Data
- Neutrophils
- Phenotype
- Polymerase Chain Reaction