Article
Determination of granulocyte-specific antigens on neutrophil FcA receptor IIIb by PCR-preferential homoduplex formation assay, and gene frequencies in the Japanese population.
Vox sanguinis - 1 Jan 1999
Fujiwara K, Watanabe Y, Mitsunaga S, Oka T, Yamane A, Akaza T, Tadokoro K, Tokunaga K, Shibata Y, Juji T
Abstract excerpt
BACKGROUND AND OBJECTIVES: Granulocyte-specific antigens play an important role in provoking immune neutropenia and transfusion reactions. We developed a new DNA-typing method, PCR-preferential homoduplex formation assay (PHFA), to determine granulocyte-specific antigens on the neutrophil Fcgamma receptor IIIb (FcgammaRIIIb, CD16b), namely, the NA1, NA2, and SH antigens and their gene frequencies in the Japanese...
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