The repertoire of cytotoxic T lymphocytes in the recognition of mutant simian immunodeficiency virus variants.

Article

The repertoire of cytotoxic T lymphocytes in the recognition of mutant simian immunodeficiency virus variants.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 1994

Shen L, Chen Z W, Letvin N L

Abstract excerpt

The importance of the repertoire of a primed, AIDS virus-specific population of CTL in the recognition of emerging mutant viruses was assessed in simian immunodeficiency virus (SIV)-infected rhesus monkeys. These studies were done by using the well-characterized CTL recognition of the SIVmac Gag...

Topics

Amino Acid Sequence
Animals
Cell Line
Cytotoxicity Tests, Immunologic
Gene Products, gag
Macaca mulatta
Molecular Sequence Data
Mutation
Simian Immunodeficiency Virus
T-Lymphocytes, Cytotoxic

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