Article
Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex.
The Journal of experimental medicine - 4 May 1998
Kuroda M J, Schmitz J E, Barouch D H, Craiu A, Allen T M, Sette A, Watkins D I, Forman M A, Letvin N L
Abstract excerpt
A tetrameric recombinant major histocompatibility complex (MHC) class I-peptide complex was used as a staining reagent in flow cytometric analyses to quantitate and define the phenotype of Gag-specific cytotoxic T lymphocytes (CTLs) in the peripheral blood of simian immunodeficiency virus macaque...
Topics
- Animals
- CD8-Positive T-Lymphocytes
- Cytotoxicity Tests, Immunologic
- Epitopes
- Flow Cytometry
- Gene Products, gag
- Histocompatibility Antigens Class I
- Macaca mulatta
- Major Histocompatibility Complex
- Phenotype
- Protein Conformation
- Recombinant Proteins
- Simian Immunodeficiency Virus