Article
Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection.
The Journal of experimental medicine - 13 Apr 2009
Price David A, Asher Tedi E, Wilson Nancy A, Nason Martha C, Brenchley Jason M, Metzler Ian S, Venturi Vanessa, Gostick Emma, Chattopadhyay Pratip K, Roederer Mario, Davenport Miles P, Watkins David I, Douek Daniel C
Abstract excerpt
Despite the pressing need for an AIDS vaccine, the determinants of protective immunity to HIV remain concealed within the complexity of adaptive immune responses. We dissected immunodominant virus-specific CD8(+) T cell populations in Mamu-A*01(+) rhesus macaques with primary SIV infection to elu...
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