Linkage analysis does not support a role for glucokinase gene in the aetiology of type 2 diabetes mellitus among north western Italians.

doi:10.1016/0303-7207(94)90117-1

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Article

Linkage analysis does not support a role for glucokinase gene in the aetiology of type 2 diabetes mellitus among north western Italians.

Molecular and cellular endocrinology - 1 Sept 1994

Laurino C, Bertolini S, Cordera R

Abstract excerpt

The contribution of a 3' glucokinase gene polymorphism to the aetiology of type 2 diabetes mellitus was studied in 17 diabetic pedigrees from North-Western Italy; linkage methodology was used. A CA repeat sequence was employed as a marker and amplified by PCR. Three alleles were found: Z (195 bp)...

Topics

Alleles
Base Sequence
Diabetes Mellitus, Type 2
Genetic Linkage
Genotype
Glucokinase
Humans
Italy
Lod Score
Molecular Sequence Data
Pedigree
Polymerase Chain Reaction
Polymorphism, Genetic
Repetitive Sequences, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 7988743
DOI: 10.1016/0303-7207(94)90117-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7988743-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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