Article
Glucokinase gene polymorphisms: a genetic marker for glucose intolerance in a cohort of elderly Finnish men.
Diabetic medicine : a journal of the British Diabetic Association - 1 Mar 1994
McCarthy M I, Hitman G A, Hitchins M, Riikonen A, Stengård J, Nissinen A, Tuomilehto-Wolf E, Tuomilehto J
Abstract excerpt
Although mutations in the glucokinase gene are implicated in the pathogenesis of glucose intolerance in pedigrees with maturity-onset diabetes of the young, the role of such mutations in typical Type 2 diabetes is poorly characterized. We studied a cohort of elderly men born (between 1900 and 191...
Topics
- Aged
- Alleles
- Blood Glucose
- Cohort Studies
- DNA
- DNA, Satellite
- Diabetes Mellitus, Type 2
- Finland
- Genetic Markers
- Genotype
- Glucokinase
- Glucose Intolerance
- Glucose Tolerance Test
- Haplotypes
- Humans