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Article

Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).

1 Dec 1994

Abstract excerpt

Recent reports (Raynor et al) have claimed the identification of potent somatostatin (SST) agonists exhibiting binding affinities of 1-2 pM and up to 30,000 fold binding selectivity for several of the 5 cloned sstr subtypes. These conclusions, however, are based on binding comparisons of sstr subtypes from different species expressed in different cell lines and studied with different radioligands. To eliminate...

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Identifiers

PMID: 7988476
DOI: 10.1210/endo.135.6.7988476

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