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Article

Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.

Endocrine - 1 Nov 2002

Angelova Krassimira, Puett David

Abstract excerpt

The glycoprotein hormone receptors-luteinizing hormone receptor (LHR), follicle-stimulating hormone receptor (FSHR), and thyroid-stimulating hormone receptor (TSHR)--are G-protein-coupled receptors with an invariant 10-amino acid residue sequence in the ectodomain proximal to transmembrane helix 1. A Glu-Asp, located at the midpoint of this conserved sequence, has been suggested to be important in ligand-mediated...

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Source

Identifiers

PMID: 12588044
DOI: 10.1385/ENDO:19:2:147

Genes

FSHR
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.PMID 12588044Read ↗

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Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling.Semantic proximity Read ↗

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